Oven-Baked Chicken Breast Casserole with Spinach and Sun-Dried Tomatoes
This Oven-Baked Chicken Breast Casserole is a dish that combines creamy, cheesy goodness with the freshness of spinach and the tangy bite of sun-dried tomatoes. The moist, tender chicken breasts are baked to perfection in a flavorful broth, topped with melted mozzarella, and garnished with fresh herbs and cherry tomatoes for a dish that is both hearty and elegant.
I love making this Baked Tuscan Chicken Casserole for family dinners or meal prep because it’s easy to prepare, full of flavor, and looks impressive on the table. Whether you’re craving a comforting Italian-inspired meal or looking for a creamy, protein-packed dish, this chicken spinach sun-dried tomato recipe is a must-try!
Prep and Cooking Details
| Preparation Time | Total Cooking Time | Number of Servings |
|---|---|---|
| 10 minutes | 30 minutes | 4 servings |
Ingredients for My Oven-Baked Chicken Breast Casserole
- 4 boneless, skinless chicken breasts
- 2 cups fresh spinach
- 1 cup cherry tomatoes, halved
- 1/2 cup sun-dried tomatoes, chopped
- 1 cup mozzarella cheese, shredded
- 1/2 cup chicken broth
- 2 tablespoons olive oil
- 1 teaspoon garlic powder
- 1 teaspoon Italian seasoning
- Salt and pepper to taste
Pro Tips for Success
- Sear the chicken first – This adds a golden crust and locks in moisture.
- Use high-quality mozzarella – Freshly shredded cheese melts better than pre-shredded.
- Don’t overbake – Chicken dries out quickly; use a thermometer and remove at 165°F (75°C).
- Add extra spinach if desired – It wilts down significantly during baking.
- Serve with pasta or rice – This dish pairs beautifully with a side of buttery pasta, mashed potatoes, or cauliflower rice for a low-carb option.
Tools You’ll Need
- Large skillet
- Baking dish (9×13 inches)
- Measuring cups and spoons
- Cutting board and knife
- Tongs
- Aluminum foil (optional for covering)
Substitutions and Variations
| Substitution | Original Ingredient | New Flavor Profile |
|---|---|---|
| Feta cheese | Mozzarella | Adds a tangy, salty flavor |
| Basil leaves | Spinach | A fresh and fragrant twist |
| Heavy cream | Chicken broth | Creates a richer, silkier sauce |
| Mushrooms | Cherry tomatoes | A deep, earthy umami taste |
Make-Ahead Tips
- Marinate the chicken ahead – Toss with olive oil, garlic powder, and Italian seasoning for extra flavor.
- Assemble the casserole the night before – Cover and refrigerate, then bake when ready.
- Freeze for later – Store in an airtight container for up to 3 months.
Step-by-Step Instructions for a Perfect Oven-Baked Chicken Breast Casserole
Step 1: Preheat & Prepare
- Preheat the oven to 375°F (190°C).
- Grease a 9×13-inch baking dish with olive oil.
Step 2: Sear the Chicken
- Heat 1 tablespoon of olive oil in a large skillet over medium-high heat.
- Season chicken breasts with salt, pepper, and garlic powder.
- Sear each side for 2-3 minutes, until golden brown.
- Remove from heat and set aside.
Step 3: Assemble the Casserole
- Place fresh spinach in the bottom of the baking dish.
- Layer the seared chicken breasts on top.
- Scatter cherry tomatoes and sun-dried tomatoes around the dish.
- Pour chicken broth over everything for extra moisture.
- Sprinkle shredded mozzarella evenly over the top.
Step 4: Bake the Casserole
- Cover with foil and bake for 20 minutes.
- Uncover and bake for another 5-10 minutes, until cheese is bubbly and golden.
Step 5: Garnish & Serve
- Let the casserole rest for 5 minutes.
- Garnish with fresh basil or parsley.
- Serve warm with your favorite side dish.
Suggested Drink Pairing
A light Chardonnay complements the creamy, cheesy flavors of this casserole. If you prefer a non-alcoholic option, try a lemon-infused sparkling water to balance the richness.
Enjoy!
This Baked Tuscan Chicken Casserole is a simple, flavorful dish that’s perfect for weeknight meals or special occasions. Give it a try and let me know how you love it! 🍗🍅✨
